We understand that living with chronic back pain is difficult. When you’re unable to function normally, it’s hard to stay optimistic. We are here to answer your questions, deliver extraordinary care, and help you make informed treatment decisions.

We have always treated surgery as a last option, and this has been the foundation of our practice. Over 75% of our patients are treated successfully without any surgical intervention. However, we will deliver the most advanced and minimally invasive treatment options that are available, if surgical intervention ever becomes necessary.

At the Tampa Back Institute, you will receive a comprehensive evaluation of your spine and a treatment plan tailored to individual conditions, needs and lifestyles. We are passionate about helping our patients and committed to providing the most state-of-the-art surgical procedures or alternative treatment solutions.


Mark Nicholas Perenich, D.O., a board certified orthopedic surgeon, who was fellowship trained by world recognized surgeons at the Texas Back Institute, partnered with his wife to create Tampa Back Institute. Dr. Perenich specializes in using minimally invasive techniques that greatly reduce the impact of surgery on the body. Therefore, our patients commonly enjoy more predictable surgical outcomes, faster recovery times, and a quicker return to work and hobbies.

Moreover, Dr. Perenich was born and raised in the Tampa Bay area. He earned his Bachelor of Science in Biochemistry from Florida State University. He then continued his education at the Philadelphia College of Osteopathic Medicine where he completed Graduate and Medical School. After that, Dr. Perenich completed a one year internship program followed by a four year residency program at Largo Medical Center where he served as the Chief Resident. During residency, Dr. Perenich completed rotations with nationally recognized spine surgeons in the Tampa Bay area.

Additionally, Dr. Perenich completed over 600 surgeries under the supervision of world recognized surgeons during his spine fellowship program at the prestigious Texas Back Institute in Plano, TX. Additionally, he participated in various surgical technique courses, including Minimally Invasive Spine Surgery and the American Academy of Orthopedic Surgery State of the Art Spine Surgery course. Dr. Perenich’s focus was spine trauma, scoliosis, and disc replacement surgery. Along with Dr. Perenich’s academic accomplishments, he has also been the recipient of numerous grants and awards, as well as being published in an academic journal.


  • Regenerative Medicine using Stem Cells, PRP, or Biological Tissue Grafts 
  • Modern, Non-Operative Treatment Options 
  • Minimally Invasive Spine Surgery 
  • Less than 1 inch incisions 
  • Robotic-assisted surgeries for precise accuracy
  • Faster recovery and better results
  • Complex and Revision Spine Surgery
  • In-network hospital stay or same-day outpatient surgery
Medium shot picture of Dr. Mark Nicholas Perenich, D.O.

Dr. Mark Nicholas Perenich, D.O.

Mark Nicholas Perenich, D.O., a board certified orthopedic surgeon, was fellowship trained by world recognized surgeons at the Texas Back Institute. He is a published author, mentor, and speaker on disorders of the spine as well as unique surgical approaches.